21-P017 Notch signaling in pulmonary epithelial cell differentiation

نویسندگان

  • Michaela Mai
  • Oliver Dittrich-Breiholz
  • Michael Kracht
  • Achim Gossler
چکیده

Axin2 loss, we are over-expressing a drug-stabilised b-catenin construct in wild-type skull osteoblast cultures, and in skull explant (calvarial) cultures. Using a drug-dependent b-catenin will allow us to investigate the threshold levels of Wnt signalling required for ossification and the stages at which the b-catenin signal is critical for osteoblast differentiation. Our findings from these investigations will be reported here.

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عنوان ژورنال:
  • Mechanisms of Development

دوره 126  شماره 

صفحات  -

تاریخ انتشار 2009